User blog comment:A Wikia Contributor 9337/Heavy build explanation/@comment-27374562-20151222012552/@comment-27374562-20151223011507

That's still not a lot of Regen for the Skill Points spent and Armor slots used, when tankiness is present. You can get over 10 times that from a Bio Shocky against the right horde, and a Bio Tempest wouldn't be too far behind that. You could literally just hit HTL, stand still, spray the crowd, and fill up your entire HP in a few seconds; and you would still have all the bonuses from wherever else you put those Skill Points, and you could have more defensive Augs on your Armor.

Honestly, building a solid Regenerator (one who can recover 50%+ of their HP in between Waves on Apoc, for instance) is not really a possibility with Skill Points and Armor alone. NK would have to rebalance those buffs against the massive boost you get from the right Bio-Aug'd Weapons, since HR and Tissue Repair really only amount to negligible gains compared to multi-projectile Bio guns. But again, that's just been my experience on Mobile. I plan on focusing on Skill- and Armor-based regeneration for my Medic when I finally get around to playing him again, so I may discover otherwise by the time he's a Final Build; but so far that I've found, Bio guns trump HR and TR.